Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC3962085 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Li Xiaoman X Zhang Ziding Z Song Jiangning J
Computational and structural biotechnology journal 20121017
Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of enzyme-based practical applications and that of naturally occurring enzymes. Multiple experimental approaches have been applied to generate nearly all possible mutations of target enzymes, allowing the identification of desirable variants with improved properties to meet the practical needs. Meanwhile, an increasing number of computational methods have been developed to assist in the modification ...[more]