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Recipient-related clinical risk factors for primary graft dysfunction after lung transplantation: a systematic review and meta-analysis.


ABSTRACT:

Background

Primary graft dysfunction (PGD) is the main cause of early morbidity and mortality after lung transplantation. Previous studies have yielded conflicting results for PGD risk factors. Herein, we carried out a systematic review and meta-analysis of published literature to identify recipient-related clinical risk factors associated with PGD development.

Method

A systematic search of electronic databases (PubMed, Embase, Web of Science, Cochrane CENTRAL, and Scopus) for studies published from 1970 to 2013 was performed. Cohort, case-control, or cross-sectional studies that examined recipient-related risk factors of PGD were included. The odds ratios (ORs) or mean differences (MDs) were calculated using random-effects models.

Result

Thirteen studies involving 10

SUBMITTER: Liu Y 

PROVIDER: S-EPMC3962459 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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