Ontology highlight
ABSTRACT:
SUBMITTER: Mayer IA
PROVIDER: S-EPMC3962777 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Mayer Ingrid A IA Abramson Vandana G VG Lehmann Brian D BD Pietenpol Jennifer A JA
Clinical cancer research : an official journal of the American Association for Cancer Research 20140201 4
Triple-negative breast cancer (TNBC) is a heterogeneous disease; gene expression analyses recently identified six distinct TNBC subtypes, each displaying a unique biology. Exploring novel approaches to treatment of these subtypes is critical because less than 30% of women with metastatic breast cancer survive five years and virtually all women with metastatic TNBC will ultimately die of their disease despite systemic therapy. To date, not a single targeted therapy has been approved for the treat ...[more]