Anterior cingulate GABA levels predict whole-brain cerebral blood flow.
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ABSTRACT:
SUBMITTER: Krause BW
PROVIDER: S-EPMC3963135 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Anterior cingulate GABA levels predict whole-brain cerebral blood flow.
Krause Benjamin W BW Wijtenburg S Andrea SA Holcomb Henry H HH Kochunov Peter P Wang Danny J J DJ Hong L Elliot LE Rowland Laura M LM
Neuroscience letters 20140104
This study examined the relationship of γ-aminobutyric acid (GABA) and glutamate levels from the anterior and posterior cingulates (AC and PC) with cerebral blood flow (CBF) at rest. (1)H magnetic resonance spectroscopy measurements in the AC and PC and pseudo-continuous arterial spin labeling data were acquired from 10 healthy controls. GABA levels from the AC were strongly inversely correlated with global (whole-brain) CBF (r=-0.91, p=0.0015). GABA levels from the PC and glutamate levels from ...[more]
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