Ontology highlight
ABSTRACT:
SUBMITTER: Legendre M
PROVIDER: S-EPMC3964051 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Legendre Matthieu M Bartoli Julia J Shmakova Lyubov L Jeudy Sandra S Labadie Karine K Adrait Annie A Lescot Magali M Poirot Olivier O Bertaux Lionel L Bruley Christophe C Couté Yohann Y Rivkina Elizaveta E Abergel Chantal C Claverie Jean-Michel JM
Proceedings of the National Academy of Sciences of the United States of America 20140303 11
The largest known DNA viruses infect Acanthamoeba and belong to two markedly different families. The Megaviridae exhibit pseudo-icosahedral virions up to 0.7 μm in diameter and adenine-thymine (AT)-rich genomes of up to 1.25 Mb encoding a thousand proteins. Like their Mimivirus prototype discovered 10 y ago, they entirely replicate within cytoplasmic virion factories. In contrast, the recently discovered Pandoraviruses exhibit larger amphora-shaped virions 1 μm in length and guanine-cytosine-ric ...[more]