Aspects of Therapy for Cervical Cancer in Germany 2012 - Results from a Survey of German Gynaecological Hospitals.
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ABSTRACT: Introduction: In spite of the existence of guidelines and international recommendations, many aspects in the diagnosis, therapy and follow-up of patients with cervical cancer are not based on validated data. A broad spectrum of different opinions and procedures concerning the therapy for patients with cervical cancer is under controversial discussion by the responsible gynaecologists in German hospitals. Methods: The present study is intended to picture the current treatment situation for cervical cancer in Germany. For this purpose a specially developed questionnaire with questions divided into 19 subsections was sent to all 688 gynaecological hospitals in Germany. Results: The response rate to the questionnaire was 34?%. 91?% of the hospitals treated between 0 and 25 patients with cervical cancer per year. 7.5?% treated between 26 and 50 and 1.4?% of the hospitals more than 50 patients per year. The bimanual examination was the most frequently used staging method (98?%); PET-CT was the least used staging method (2.3?%). Interestingly 48?% of the hospitals used surgical staging. The great majority of the hospitals (71?%) used abdominal radical hysterectomy (Wertheim-Meigs operation) to treat their patients. TMMR via laparotomy was used by 13?%. 16?% of the hospitals performed laparoscopic or robot-assisted radical hysterectomies. The sentinel concept was hardly used even in the early stages. It must be emphasised that in 74?% of the hospitals radical hysterectomies were performed even in cases with positive pelvic lymph nodes and in 43?% also in cases with positive paraaortic lymph nodes. The therapy of choice for FIGO IIB cancers is primary radiochemotherapy (RCTX) in 21?% of the hospitals; operative staging followed by radiochemotherapy in 24?% and treatment by radical hysterectomy followed by adjuvant RCTX was employed in this situation by 46?% of the hospitals. In 15-97?% of the hospitals for node-negative and in sano resected patients in stage pT1B1/1B2 after radical hysterectomy, an adjuvant RCTX is recommended when further risk factors exist (LVSI, tumour >?4?cm, age Conclusion: A broad spectrum of differing staging and therapy concepts is in use for patients with cervical cancer in Germany. A standardisation of therapy is needed. An update of national guidelines could help to achieve more transparency and a standardisation of treatment for patients with cervical cancer.
SUBMITTER: Mangler M
PROVIDER: S-EPMC3964377 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
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