Unknown

Dataset Information

0

3did: a catalog of domain-based interactions of known three-dimensional structure.


ABSTRACT: The database of 3D interacting domains (3did, available online for browsing and bulk download at http://3did.irbbarcelona.org) is a catalog of protein-protein interactions for which a high-resolution 3D structure is known. 3did collects and classifies all structural templates of domain-domain interactions in the Protein Data Bank, providing molecular details for such interactions. The current version also includes a pipeline for the discovery and annotation of novel domain-motif interactions. For every interaction, 3did identifies and groups different binding modes by clustering similar interfaces into 'interaction topologies'. By maintaining a constantly updated collection of domain-based structural interaction templates, 3did is a reference source of information for the structural characterization of protein interaction networks. 3did is updated every 6 months.

SUBMITTER: Mosca R 

PROVIDER: S-EPMC3965002 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

3did: a catalog of domain-based interactions of known three-dimensional structure.

Mosca Roberto R   Céol Arnaud A   Stein Amelie A   Olivella Roger R   Aloy Patrick P  

Nucleic acids research 20130929 Database issue


The database of 3D interacting domains (3did, available online for browsing and bulk download at http://3did.irbbarcelona.org) is a catalog of protein-protein interactions for which a high-resolution 3D structure is known. 3did collects and classifies all structural templates of domain-domain interactions in the Protein Data Bank, providing molecular details for such interactions. The current version also includes a pipeline for the discovery and annotation of novel domain-motif interactions. Fo  ...[more]

Similar Datasets

| S-EPMC3013799 | biostudies-literature
| S-EPMC539991 | biostudies-literature
| S-EPMC2686500 | biostudies-literature
| S-EPMC2761005 | biostudies-literature
| S-EPMC2238836 | biostudies-literature
| S-EPMC3136784 | biostudies-literature
| S-EPMC5429643 | biostudies-literature
| S-EPMC3013741 | biostudies-literature
| S-EPMC1370687 | biostudies-literature
| S-EPMC2930738 | biostudies-literature