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HoPaCI-DB: host-Pseudomonas and Coxiella interaction database.

ABSTRACT: Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host-pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between molecules, bioprocesses and cellular structures extracted from the scientific literature. Systematic annotation and interactive graphical representation of disease networks make HoPaCI-DB a versatile knowledge base for biologists and network biology approaches.

SUBMITTER: Bleves S

PROVIDER: S-EPMC3965080 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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HoPaCI-DB: host-Pseudomonas and Coxiella interaction database.

Bleves Sophie S Dunger Irmtraud I Walter Mathias C MC Frangoulidis Dimitrios D Kastenmüller Gabi G Voulhoux Romé R Ruepp Andreas A

Nucleic acids research 20131016 Database issue

Bacterial infectious diseases are the result of multifactorial processes affected by the interplay between virulence factors and host targets. The host-Pseudomonas and Coxiella interaction database (HoPaCI-DB) is a publicly available manually curated integrative database (http://mips.helmholtz-muenchen.de/HoPaCI/) of host-pathogen interaction data from Pseudomonas aeruginosa and Coxiella burnetii. The resource provides structured information on 3585 experimentally validated interactions between ...[more]

PMID: 24137008

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