Ontology highlight
ABSTRACT:
SUBMITTER: An P
PROVIDER: S-EPMC3965585 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
An Ping P Miljkovic Iva I Thyagarajan Bharat B Kraja Aldi T AT Daw E Warwick EW Pankow James S JS Selvin Elizabeth E Kao W H Linda WH Maruthur Nisa M NM Nalls Micahel A MA Liu Yongmei Y Harris Tamara B TB Lee Joseph H JH Borecki Ingrid B IB Christensen Kaare K Eckfeldt John H JH Mayeux Richard R Perls Thomas T TT Newman Anne B AB Province Michael A MA
Metabolism: clinical and experimental 20131204 4
<h4>Objective</h4>Glycated hemoglobin (HbA1c) is a stable index of chronic glycemic status and hyperglycemia associated with progressive development of insulin resistance and frank diabetes. It is also associated with premature aging and increased mortality. To uncover novel loci for HbA1c that are associated with healthy aging, we conducted a genome-wide association study (GWAS) using non-diabetic participants in the Long Life Family Study (LLFS), a study with familial clustering of exceptional ...[more]