Ontology highlight
ABSTRACT:
SUBMITTER: Wurpel DJ
PROVIDER: S-EPMC3966885 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wurpel Daniël J DJ Totsika Makrina M Allsopp Luke P LP Hartley-Tassell Lauren E LE Day Christopher J CJ Peters Kate M KM Sarkar Sohinee S Ulett Glen C GC Yang Ji J Tiralongo Joe J Strugnell Richard A RA Jennings Michael P MP Schembri Mark A MA
PloS one 20140326 3
Uropathogenic Escherichia coli (UPEC) is the leading causative agent of urinary tract infections (UTI) in the developed world. Among the major virulence factors of UPEC, surface expressed adhesins mediate attachment and tissue tropism. UPEC strains typically possess a range of adhesins, with type 1 fimbriae and P fimbriae of the chaperone-usher class the best characterised. We previously identified and characterised F9 as a new chaperone-usher fimbrial type that mediates biofilm formation. Howev ...[more]