Ontology highlight
ABSTRACT:
SUBMITTER: Bavarsad Shahripour R
PROVIDER: S-EPMC3967529 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Bavarsad Shahripour Reza R Harrigan Mark R MR Alexandrov Andrei V AV
Brain and behavior 20140113 2
<h4>Background</h4>There is an expanding field of research investigating the benefits of medicines with multiple mechanisms of action across neurological disorders. N-acetylcysteine (NAC), widely known as an antidote to acetaminophen overdose, is now emerging as treatment of vascular and nonvascular neurological disorders. NAC as a precursor to the antioxidant glutathione modulates glutamatergic, neurotrophic, and inflammatory pathways.<h4>Aim and discussion</h4>Most NAC studies up to date have ...[more]