Ontology highlight
ABSTRACT:
SUBMITTER: Ma C
PROVIDER: S-EPMC3967758 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Ma Chao C Wang Lirong L Yang Peng P Myint Kyaw Z KZ Xie Xiang-Qun XQ
Journal of chemical information and modeling 20130115 1
The cannabinoid receptor subtype 2 (CB2) is a promising therapeutic target for blood cancer, pain relief, osteoporosis, and immune system disease. The recent withdrawal of Rimonabant, which targets another closely related cannabinoid receptor (CB1), accentuates the importance of selectivity for the development of CB2 ligands in order to minimize their effects on the CB1 receptor. In our previous study, LiCABEDS (Ligand Classifier of Adaptively Boosting Ensemble Decision Stumps) was reported as a ...[more]