Structure of allergens and structure based epitope predictions.
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ABSTRACT:
SUBMITTER: Dall'antonia F
PROVIDER: S-EPMC3969231 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Publications
Structure of allergens and structure based epitope predictions.
Dall'antonia Fabio F Pavkov-Keller Tea T Zangger Klaus K Keller Walter W
Methods (San Diego, Calif.) 20130723 1
The structure determination of major allergens is a prerequisite for analyzing surface exposed areas of the allergen and for mapping conformational epitopes. These may be determined by experimental methods including crystallographic and NMR-based approaches or predicted by computational methods. In this review we summarize the existing structural information on allergens and their classification in protein fold families. The currently available allergen-antibody complexes are described and the e ...[more]
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