Structural organisation of the type IV secretion systems.
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ABSTRACT:
SUBMITTER: Waksman G
PROVIDER: S-EPMC3969286 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Structural organisation of the type IV secretion systems.
Waksman Gabriel G Orlova Elena V EV
Current opinion in microbiology 20131205
Type IV secretion (T4S) systems are large dynamic nanomachines that transport DNAs and/or proteins through the membranes of bacteria. Because of their complexity and multi-protein organisation, T4S systems have been extremely challenging to study structurally. However in the past five years significant milestones have been achieved by X-ray crystallography and cryo-electron microscopy. This review describes some of the more recent advances: the structures of some of the protein components of the ...[more]
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