Intake of fruit juice and incidence of type 2 diabetes: a systematic review and meta-analysis.

ABSTRACT: BACKGROUND: Several prospective studies have been conducted to examine the relationship between fruit juice intake and risk of incident type 2 diabetes, but results have been mixed. In the present study, we aimed to estimate the association between fruit juice intake and risk of type 2 diabetes. METHODS: PubMed and Embase databases were searched up to December 2013. All prospective cohort studies of fruit juice intake with risk of type 2 diabetes were included. The pooled relative risks (RRs) with 95% confidence intervals (CIs) for highest vs. lowest category of fruit juice intake were estimated using a random-effects model. RESULTS: A total of four studies (191,686 participants, including 12,375 with type 2 diabetes) investigated the association between sugar-sweetened fruit juice and risk of incident type 2 diabetes, and four studies (137,663 participants and 4,906 cases) investigated the association between 100% fruit juice and risk of incident type 2 diabetes. A higher intake of sugar-sweetened fruit juice was significantly associated with risk of type 2 diabetes (RR?=?1.28, 95%CI?=?1.04-1.59, p?=?0.02), while intake of 100% fruit juice was not associated with risk of developing type 2 diabetes (RR?=?1.03, 95% CI?=?0.91-1.18, p?=?0.62). CONCLUSIONS: Our findings support dietary recommendations to limit sugar-sweetened beverages, such as fruit juice with added sugar, to prevent the development of type 2 diabetes.

SUBMITTER: Xi B 

PROVIDER: S-EPMC3969361 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature