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Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method: a time-lapse study.

ABSTRACT:

Purpose

To analyze the cleavage patterns in dipronuclear (2PN) and tripronuclear (3PN) embryos in relation to fertilization method.

Method

Time-lapse analysis.

Results

Compared to 2PN, more 3PN IVF embryos displayed early cleavage into 3 cells (p?ConclusionsThis study reports differences in cleavage patterns between 2PN and 3PN embryos and for the first time demonstrates differences in the cleavage pattern between 3PN IVF and ICSI embryos.

SUBMITTER: Joergensen MW

PROVIDER: S-EPMC3969464 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Altered cleavage patterns in human tripronuclear embryos and their association to fertilization method: a time-lapse study.

Joergensen Mette Warming MW Agerholm Inge I Hindkjaer Johnny J Bolund Lars L Sunde Lone L Ingerslev Hans Jakob HJ Kirkegaard Kirstine K

Journal of assisted reproduction and genetics 20140124 4

<h4>Purpose</h4>To analyze the cleavage patterns in dipronuclear (2PN) and tripronuclear (3PN) embryos in relation to fertilization method.<h4>Method</h4>Time-lapse analysis.<h4>Results</h4>Compared to 2PN, more 3PN IVF embryos displayed early cleavage into 3 cells (p < 0.001), displayed longer duration of the 3-cell stage (p < 0.001), and arrested development from the compaction stage and onwards (p < 0.001). For the IVF embryos, the 2nd and 3rd cleavage cycles were completed within the expecte ...[more]

PMID: 24458469

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