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Exceptionally fast carbon-carbon bond reductive elimination from gold(III).

ABSTRACT: Reductive elimination of carbon-carbon bonds occurs in numerous metal-catalysed reactions. This process is well documented for a variety of transition metal complexes. However, carbon-carbon bond reductive elimination from a limited number of Au(III) complexes has been shown to be a slow and prohibitive process that generally requires elevated temperatures. Herein we show that oxidation of a series of mono- and bimetallic Au(I) aryl complexes at low temperature generates observable Au(III) and Au(II) intermediates. We also show that aryl-aryl bond reductive elimination from these oxidized species is not only among the fastest observed for any transition metal, but is also mechanistically distinct from previously studied alkyl-alkyl and aryl-alkyl reductive eliminations from Au(III).

SUBMITTER: Wolf WJ

PROVIDER: S-EPMC3970324 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Exceptionally fast carbon-carbon bond reductive elimination from gold(III).

Wolf William J WJ Winston Matthew S MS Toste F Dean FD

Nature chemistry 20131222 2

Reductive elimination of carbon-carbon bonds occurs in numerous metal-catalysed reactions. This process is well documented for a variety of transition metal complexes. However, carbon-carbon bond reductive elimination from a limited number of Au(III) complexes has been shown to be a slow and prohibitive process that generally requires elevated temperatures. Herein we show that oxidation of a series of mono- and bimetallic Au(I) aryl complexes at low temperature generates observable Au(III) and A ...[more]

PMID: 24451593

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