Ontology highlight
ABSTRACT:
SUBMITTER: Pollack IF
PROVIDER: S-EPMC3972122 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Pollack Ian F IF Jakacki Regina I RI Butterfield Lisa H LH Okada Hideho H
Expert review of neurotherapeutics 20131001 10
Ependymomas are among the most challenging childhood brain tumors. Although 50-70% of ependymomas are cured with surgery and irradiation, a significant percentage of tumors recur. Ependymomas that are not amenable to complete resection at diagnosis have a particularly poor prognosis, and the vast majority of affected children experience tumor recurrence. Although transient responses have been observed in recurrent tumors treated with re-irradiation and several chemotherapy regimens, long-term di ...[more]