Dataset Information

Motor events during healthy sleep: a quantitative polysomnographic study.

ABSTRACT:

Study objectives

Many sleep disorders are characterized by increased motor activity during sleep. In contrast, studies on motor activity during physiological sleep are largely lacking. We quantitatively investigated a large range of motor phenomena during polysomnography in physiological sleep.

Design

Prospective polysomnographic investigation.

Setting

Academic referral sleep laboratory.

Participants

One hundred healthy sleepers age 19-77 y were strictly selected from a representative population sample by a two-step screening procedure.

Interventions

N/A.

Measurements and results

Polysomnography according to American Academy of Sleep Medicine (AASM) standards was performed, and quantitative normative values were established for periodic limb movements in sleep (PLMS), high frequency leg movements (HFLM), fragmentary myoclonus (FM), neck myoclonus (NM), and rapid eye movement (REM)-related electromyographic (EMG) activity. Thirty-six subjects had a PLMS index > 5/h, 18 had a PLMS index > 15/h (90th percentile: 24.8/h). Thirty-three subjects had HFLM (90th percentile: four sequences/night). All subjects had FM (90th percentile 143.7/h sleep). Nine subjects fulfilled AASM criteria for excessive FM. Thirty-five subjects had NM (90th percentile: 8.8/h REM sleep). For REM sleep, different EMG activity measures for the mentalis and flexor digitorum superficialis muscles were calculated: the 90th percentile for phasic mentalis EMG activity for 30-sec epochs according to AASM recommendation was 15.6%, and for tonic mentalis EMG activity 2.6%. Twenty-five subjects exceeded the recently proposed phasic mentalis cutoff of 11%. None of the subjects exceeded the tonic mentalis cutoff of 9.6%.

Conclusion

Quantification of motor phenomena is a basic prerequisite to develop normative values, and is a first step toward a more precise description of the various motor phenomena present during sleep. Because rates of motor events were unexpectedly high even in physiological sleep, the future use of normative values for both research and clinical routine is essential.

SUBMITTER: Frauscher B

PROVIDER: S-EPMC3972421 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Publications

Motor events during healthy sleep: a quantitative polysomnographic study.

Frauscher Birgit B Gabelia David D Mitterling Thomas T Biermayr Marlene M Bregler Deborah D Ehrmann Laura L Ulmer Hanno H Högl Birgit B

Sleep 20140401 4

<h4>Study objectives</h4>Many sleep disorders are characterized by increased motor activity during sleep. In contrast, studies on motor activity during physiological sleep are largely lacking. We quantitatively investigated a large range of motor phenomena during polysomnography in physiological sleep.<h4>Design</h4>Prospective polysomnographic investigation.<h4>Setting</h4>Academic referral sleep laboratory.<h4>Participants</h4>One hundred healthy sleepers age 19-77 y were strictly selected fro ...[more]

PMID: 24744455

Similar Datasets

Project description:Study objectivesVideo-polysomnography (v-PSG) is the gold standard for the diagnosis of sleep disorders. Quantitative assessment of type and distribution of physiological movements during sleep for the differentiation between physiological and pathological motor activity is lacking. We performed a systematic and detailed analysis of movements during physiological sleep using v-PSG technology.DesignProspective v-PSG investigation.SettingAcademic referral center sleep laboratory.ParticipantsOne hundred healthy sleepers aged 19-77 years recruited from a representative population sample after a two-step screening.InterventionsN/A.Measurements and resultsAll subjects underwent v-PSG. In all cases where electromyographic activity > 100 msec duration was visible during sleep in the mentalis, submentalis, flexor digitorum superficialis, or anterior tibialis muscles, the time-synchronized video was analyzed. Visible movements were classified according to movement type and topography, and movement rates were computed for the different sleep stages. A total of 9,790 movements (median 10.2/h, IQR 4.6-16.2) were analyzed: 99.7% were elementary, 0.3% complex. Movement indices were higher in men than women (men: median 13/h, interquartile range 7.1-29.3, women: median 7.9/h, interquartile range 3.4-14.5; P = 0.006). The majority of movements involved the extremities (87.9%) and were classified as focal (53.3%), distal (79.6%), and unilateral (71.5%); 15.3% of movements were associated with arousals. REM-related movements (median 0.8 sec, IQR 0.5-1.2) were shorter than NREM-related movements (median 1.1 sec, IQR 0.8-1.6; P = 0.001). Moreover, REM-related movements were predominantly myocloniform (86.6%), whereas NREM-related movements were more often non-myocloniform (59.1%, P < 0.001).ConclusionMinor movements are frequent during physiological sleep, and are associated with low arousal rates. REM-related movements were predominantly myocloniform and shorter than NREM movements, indicating different influences on motor control during both sleep states.

Dataset Information

Motor events during healthy sleep: a quantitative polysomnographic study.

Study objectives

Design

Setting

Participants

Interventions

Measurements and results

Conclusion

Publications

Motor events during healthy sleep: a quantitative polysomnographic study.

Similar Datasets

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