Ontology highlight
ABSTRACT:
SUBMITTER: Wakayama Y
PROVIDER: S-EPMC3972427 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Wakayama Yoshihiro Y Hirako Satoshi S Ogawa Tetsuo T Jimi Takahiro T Shioda Seiji S
Acta histochemica et cytochemica 20140222 1
Aquaporin (AQP) is suggested to be regulated by leptin through the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway. AQP7 and AQP9 are membrane proteins with water and glycerol channels, the latter of which is essential for triglyceride synthesis. We conjectured that the expression of AQP7 and AQP9 would be altered in the skeletal myofibers in obese leptin deficient ob/ob mice as compared with that of wild mice. RNA and protein levels were studied in the quadriceps femoris ...[more]