Ontology highlight
ABSTRACT:
SUBMITTER: Huang YZ
PROVIDER: S-EPMC3972505 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Scientific reports 20140402
Zinc finger, BED-type containing 6 (ZBED6) is an important transcription factor in placental mammals, affecting development, cell proliferation and growth. In this study, we found that the expression of the ZBED6 and IGF2 were upregulated during C2C12 differentiation. The IGF2 expression levels were negatively associated with the methylation status in beef cattle (P < 0.05). A luciferase assay for the IGF2 intron 3 and P3 promoter showed that the mutant-type 439 A-SNP-pGL3 in driving reporter ge ...[more]