Ontology highlight
ABSTRACT:
SUBMITTER: Punetha A
PROVIDER: S-EPMC3973291 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Punetha Ankita A Sivathanu Raveendran R Anand Baskaran B
Nucleic acids research 20131225 6
Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) in association with CRISPR-associated (Cas) proteins constitutes a formidable defense system against mobile genetic elements in prokaryotes. In type I-C, the ribonucleoprotein surveillance complex comprises only three Cas proteins, namely, Cas5d, Csd1 and Csd2. Unlike type I-E that uses Cse3/CasE for metal-independent CRISPR RNA maturation, type I-C that lacks this deputes Cas5d to process the pre-crRNA. Here, we report the promis ...[more]