Identification of the novel interacting partners of the mammalian target of rapamycin complex 1 in human CCRF-CEM and HEK293 cells.
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ABSTRACT:
SUBMITTER: Rahman H
PROVIDER: S-EPMC3975426 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Identification of the novel interacting partners of the mammalian target of rapamycin complex 1 in human CCRF-CEM and HEK293 cells.
Rahman Hazir H Qasim Muhammad M Oellerich Michael M Asif Abdul R AR
International journal of molecular sciences 20140318 3
The present study was undertaken to identify proteins that interact with the mammalian target of rapamycin complex 1 (mTORC1) to enable it to carry out its crucial cell signaling functions. Endogenous and myc-tag mTORC1 was purified, in-gel tryptic digested and then identified by nano-LC ESI Q-TOF MS/MS analysis. A total of nine novel interacting proteins were identified in both endogenous and myc-tag mTORC1 purifications. These new mTORC1 interacting partners include heterogeneous nuclear ribon ...[more]
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2011-03-22 | GSE27989 | GEO
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2011-03-22 | E-GEOD-27989 | biostudies-arrayexpress