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Ultrasensitive online SERS detection of structural isomers separated by capillary zone electrophoresis.

ABSTRACT: A mixture of structural isomers was separated and identified at nanomolar concentrations (?100,000 molecules) by incorporating capillary zone electrophoresis (CZE) with a sheath flow surface-enhanced Raman scattering (SERS) detector. Baseline resolution was obtained from three structural isomers of rhodamine using a planar silver SERS substrate, demonstrating the utility of this approach for trace chemical analysis.

SUBMITTER: Negri P

PROVIDER: S-EPMC3976900 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Ultrasensitive online SERS detection of structural isomers separated by capillary zone electrophoresis.

Negri Pierre P Flaherty Ryan J RJ Dada Oluwatosin O OO Schultz Zachary D ZD

Chemical communications (Cambridge, England) 20140301 21

A mixture of structural isomers was separated and identified at nanomolar concentrations (∼100,000 molecules) by incorporating capillary zone electrophoresis (CZE) with a sheath flow surface-enhanced Raman scattering (SERS) detector. Baseline resolution was obtained from three structural isomers of rhodamine using a planar silver SERS substrate, demonstrating the utility of this approach for trace chemical analysis. ...[more]

PMID: 24395125

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