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Contact angle changes induced by immunocomplex formation.


ABSTRACT: Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

SUBMITTER: Kim JH 

PROVIDER: S-EPMC3977604 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Contact angle changes induced by immunocomplex formation.

Kim Jong-Hoon JH   Shen Amy Q AQ   Lee Kyong-Hoon KH   Cangelosi Gerard A GA   Chung Jae-Hyun JH  

The Analyst 20140301 6


Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies. ...[more]

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