A photochemical method for determining plasma homocysteine with limited sample processing.
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ABSTRACT:
SUBMITTER: Hakuna L
PROVIDER: S-EPMC3979965 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Publications
A photochemical method for determining plasma homocysteine with limited sample processing.
Hakuna Lovemore L Escobedo Jorge O JO Lowry Mark M Barve Aabha A McCallum Naneki N Strongin Robert M RM
Chemical communications (Cambridge, England) 20140301 23
The photolytic formation of thiyl radicals allows for the selective detection of total homocysteine (tHcy) in plasma after reduction and filtering. The mechanism is based on the reduction of viologens by the α-amino carbon centred radical of Hcy generated by intramolecular hydrogen atom transfer (HAT) of its thiyl radical. ...[more]
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