Reduced growth and proliferation dynamics of nasal epithelial stem/progenitor cells in nasal polyps in vitro.
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ABSTRACT:
SUBMITTER: Yu XM
PROVIDER: S-EPMC3980221 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
Reduced growth and proliferation dynamics of nasal epithelial stem/progenitor cells in nasal polyps in vitro.
Yu Xue Min XM Li Chun Wei CW Chao Siew Shuen SS Li Ying Ying YY Yan Yan Y Zhao Xue Ning XN Yu Feng Gang FG Liu Jing J Shen Liang L Pan Xin Liang XL Shi Li L Wang De Yun de Y
Scientific reports 20140409
Basal cells in nasal epithelium have stemness/progenitor characters and play essential roles in the epithelial remodeling in nasal polyps (NP). We investigate whether the human nasal epithelial stem/progenitor cells (hNESPCs) from patients with NP are inherently distinct from those obtained from healthy controls. Epithelial basal cells were isolated and cultured for four passages from NP tissues and control nasal mucosa. hNESPCs from controls were stained positively with stem cell marker p63 and ...[more]
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