Ontology highlight
ABSTRACT:
SUBMITTER: Huttanus HM
PROVIDER: S-EPMC3982415 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Huttanus Herbert M HM Graugnard Elton E Yurke Bernard B Knowlton William B WB Kuang Wan W Hughes William L WL Lee Jeunghoon J
Biosensors & bioelectronics 20130711
A catalytic colorimetric detection scheme that incorporates a DNA-based hybridization chain reaction into gold nanoparticles was designed and tested. While direct aggregation forms an inter-particle linkage from only one target DNA strand, catalytic aggregation forms multiple linkages from a single target DNA strand. Gold nanoparticles were functionalized with thiol-modified DNA strands capable of undergoing hybridization chain reactions. The changes in their absorption spectra were measured at ...[more]