Ontology highlight
ABSTRACT:
SUBMITTER: Downey M
PROVIDER: S-EPMC3982851 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Downey Michael M Knight Britta B Vashisht Ajay A AA Seller Charles A CA Wohlschlegel James A JA Shore David D Toczyski David P DP
Current biology : CB 20130822 17
<h4>Background</h4>In eukaryotes, ribosome biosynthesis involves the coordination of ribosomal RNA and ribosomal protein (RP) production. In S. cerevisiae, the regulation of ribosome biosynthesis occurs largely at the level of transcription. The transcription factor Ifh1 binds at RP genes and promotes their transcription when growth conditions are favorable. Although Ifh1 recruitment to RP genes has been characterized, little is known about the regulation of promoter-bound Ifh1.<h4>Results</h4>W ...[more]