Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes.
Ontology highlight
ABSTRACT:
SUBMITTER: Lenhart PM
PROVIDER: S-EPMC3982866 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes.
Lenhart Patricia M PM Nguyen Thutrang T Wise Alison A Caron Kathleen M KM Herring Amy H AH Stuebe Alison M AM
American journal of perinatology 20130624 4
<h4>Objective</h4>Reduced maternal plasma levels of the peptide vasodilator adrenomedullin have been associated with adverse pregnancy outcomes. We measured the extent to which genetic polymorphisms in the adrenomedullin signaling pathway are associated with birth weight, glycemic regulation, and preeclampsia risk.<h4>Study design</h4>We genotyped 1,353 women in the Pregnancy, Infection, and Nutrition Postpartum Study for 37 ancestry-informative markers and for single-nucleotide polymorphisms in ...[more]
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