Ontology highlight
ABSTRACT:
SUBMITTER: Decensi A
PROVIDER: S-EPMC3982877 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Decensi Andrea A Sun Zhuoxin Z Guerrieri-Gonzaga Aliana A Thürlimann Beat B McIntosh Christina C Tondini Carlo C Monnier Alain A Campone Mario M Debled Marc M Schönenberger Astrid A Zaman Khalil K Johansson Harriet H Price Karen N KN Gelber Richard D RD Goldhirsch Aron A Coates Alan S AS Aebi Stefan S
Breast cancer research and treatment 20140201 2
The purpose of the study is to determine the effects of the BIG 1-98 treatments on bone mineral density. BIG 1-98 compared 5-year adjuvant hormone therapy in postmenopausal women allocated to four groups: tamoxifen (T); letrozole (L); 2-years T, 3-years L (TL); and 2-years L, 3-years T (LT). Bone mineral density T-score was measured prospectively annually by dual energy X-ray absorption in 424 patients enrolled in a sub-study after 3 (n = 150), 4 (n = 200), and 5 years (n = 74) from randomizatio ...[more]