Ontology highlight
ABSTRACT:
SUBMITTER: Wei X
PROVIDER: S-EPMC3982975 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Wei Xiaoli X Shi Xue X Kim Seongho S Patrick Jeffrey S JS Binkley Joe J Kong Maiying M McClain Craig C Zhang Xiang X
Analytical chemistry 20140207 4
A data dependent peak model (DDPM) based spectrum deconvolution method was developed for analysis of high resolution LC-MS data. To construct the selected ion chromatogram (XIC), a clustering method, the density based spatial clustering of applications with noise (DBSCAN), is applied to all m/z values of an LC-MS data set to group the m/z values into each XIC. The DBSCAN constructs XICs without the need for a user defined m/z variation window. After the XIC construction, the peaks of molecular i ...[more]