Ontology highlight
ABSTRACT:
SUBMITTER: Gao Q
PROVIDER: S-EPMC3983249 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Gao Qinglei Q Chen Caihong C Ji Teng T Wu Peng P Han Zhiqiang Z Fang Haiyan H Li Fei F Liu Yi Y Hu Wencheng W Gong Danni D Zhang Zeyu Z Wang Shixuan S Zhou Jianfeng J Ma Ding D
PloS one 20140410 4
Adenovirus 5 vectors, known respectively as, the first generation, second generation and oncolytic adenovirus, have been studied extensively in preclinical and clinical trials. However, hitherto few systemic evaluations of the efficacy and toxicity of these adenoviral vectors that have reflected the vertical history of adenovirus based cancer gene therapy strategies have been undertaken. This study has chosen Adv-TK, the well-established adjuvant treatment in cancer, and compared its efficacy an ...[more]