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Complete Genome Sequences of Nitrofurantoin-Sensitive and -Resistant Escherichia coli ST540 and ST2747 Strains.

ABSTRACT: Widespread multidrug resistance in Escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin. However, mechanisms by which resistance to nitrofurantoin emerges in E. coli are not well elucidated. Toward this aim, we sequenced two nitrofurantoin-sensitive E. coli sequence types (ST540 and ST2747) and their four nitrofurantoin-resistant derivatives generated in vitro under aerobic and anaerobic growth conditions.

SUBMITTER: Xavier BB 

PROVIDER: S-EPMC3983296 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Complete Genome Sequences of Nitrofurantoin-Sensitive and -Resistant Escherichia coli ST540 and ST2747 Strains.

Xavier Basil Britto BB   Vervoort Jascha J   Stewardson Andrew A   Adriaenssens Niels N   Coenen Samuel S   Harbarth Stephan S   Goossens Herman H   Malhotra-Kumar Surbhi S  

Genome announcements 20140410 2

Widespread multidrug resistance in Escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin. However, mechanisms by which resistance to nitrofurantoin emerges in E. coli are not well elucidated. Toward this aim, we sequenced two nitrofurantoin-sensitive E. coli sequence types (ST540 and ST2747) and their four nitrofurantoin-resistant derivatives generated in vitro under aerobic and anaerobic growth conditions. ...[more]

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