Template-based structure modeling of protein-protein interactions.
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ABSTRACT:
SUBMITTER: Szilagyi A
PROVIDER: S-EPMC3984454 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Template-based structure modeling of protein-protein interactions.
Szilagyi Andras A Zhang Yang Y
Current opinion in structural biology 20131211
The structure of protein-protein complexes can be constructed by using the known structure of other protein complexes as a template. The complex structure templates are generally detected either by homology-based sequence alignments or, given the structure of monomer components, by structure-based comparisons. Critical improvements have been made in recent years by utilizing interface recognition and by recombining monomer and complex template libraries. Encouraging progress has also been witnes ...[more]
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