Ontology highlight
ABSTRACT:
SUBMITTER: Zhai X
PROVIDER: S-EPMC3985921 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Zhai Xiang X Amyes Tina L TL Richard John P JP
Journal of the American Chemical Society 20140306 11
Values of (k(cat)/K(m))GAP for triosephosphate isomerase-catalyzed reactions of (R)-glyceraldehyde 3-phosphate and k(cat)/K(HPi)K(GA) for reactions of the substrate pieces glycolaldehyde and HPO3(2-) have been determined for wild-type and the following TIM mutants: I172V, I172A, L232A, and P168A (TIM from Trypanosoma brucei brucei); a 208-TGAG for 208-YGGS loop 7 replacement mutant (L7RM, TIM from chicken muscle); and, Y208T, Y208S, Y208A, Y208F and S211A (yeast TIM). A superb linear logarithmic ...[more]