Ontology highlight
ABSTRACT:
SUBMITTER: Klinshov VV
PROVIDER: S-EPMC3986068 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Klinshov Vladimir V VV Teramae Jun-nosuke JN Nekorkin Vladimir I VI Fukai Tomoki T
PloS one 20140414 4
Local cortical circuits appear highly non-random, but the underlying connectivity rule remains elusive. Here, we analyze experimental data observed in layer 5 of rat neocortex and suggest a model for connectivity from which emerge essential observed non-random features of both wiring and weighting. These features include lognormal distributions of synaptic connection strength, anatomical clustering, and strong correlations between clustering and connection strength. Our model predicts that corti ...[more]