Is radiation dose reduction the right answer for HPV-positive head and neck cancer?
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ABSTRACT:
SUBMITTER: Kimple RJ
PROVIDER: S-EPMC3986346 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
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Is radiation dose reduction the right answer for HPV-positive head and neck cancer?
Kimple Randall J RJ Harari Paul M PM
Oral oncology 20131014 6
Patients with head and neck squamous cell carcinoma (HNC) related to human papillomavirus (HPV) represent a growing and distinct patient cohort with unique molecular and epidemiologic characteristics. These patients have markedly improved survival outcomes compared to those with traditional HNC, leading some to advocate for treatment dose reduction. In this article, we review ongoing clinical trials investigating several ways to reduce therapeutic intensity for patients with HPV-positive HNC, di ...[more]
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