Ontology highlight
ABSTRACT:
SUBMITTER: Lerouge D
PROVIDER: S-EPMC3986598 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Lerouge Delphine D Rivière Alain A Dansin Eric E Chouaid Christos C Dujon Cécile C Schott Roland R Lavole Armelle A Le Pennec Vincent V Fabre Elizabeth E Crequit Jacky J Martin Francis F Dehette Stéphanie S Fournel Pierre P Precheur-Agulhon Bénédicte B Lartigau Eric E Zalcman Gérard G
BMC cancer 20140330
<h4>Background</h4>Concomitant platinum-based chemotherapy and radiotherapy (CT-RT) is the recommended treatment for unresectable locally advanced stage III non-small cell lung cancer (NSCLC). We conducted a phase II study to evaluate the efficacy and safety of fractionated oral vinorelbine with cisplatin as induction CT followed by CT-RT.<h4>Methods</h4>Patients with stage III NSCLC received 2 induction cycles of intravenous vinorelbine 25 mg/m2 and cisplatin 80 mg/m2 on day 1 and oral vinorelb ...[more]