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3D late gadolinium enhancement in a single prolonged breath-hold using supplemental oxygenation and hyperventilation.


ABSTRACT: To evaluate the feasibility of three-dimensional (3D) single breath-hold late gadolinium enhancement (LGE) of the left ventricle (LV) using supplemental oxygen and hyperventilation and compressed-sensing acceleration.Breath-hold metrics [breath-hold duration, diaphragmatic/LV position drift, and maximum variation of R wave to R wave (RR) interval] without and with supplemental oxygen and hyperventilation were assessed in healthy adult subjects using a real-time single shot acquisition. Ten healthy subjects and 13 patients then underwent assessment of the proposed 3D breath-hold LGE acquisition (field of view?=?320 × 320 × 100 mm(3) , resolution?=?1.6 × 1.6 × 5.0 mm(3) , acceleration rate of 4) and a free-breathing acquisition with right hemidiaphragm navigator (NAV) respiratory gating. Semiquantitative grading of overall image quality, motion artifact, myocardial nulling, and diagnostic value was performed by consensus of two blinded observers.Supplemental oxygenation and hyperventilation increased the breath-hold duration (35?±?11 s to 58?±?21 s; P??0.01). LGE images were of similar quality when compared with free-breathing acquisitions, but with reduced total scan time (85?±?22 s to 35?±?6 s; P?

SUBMITTER: Roujol S 

PROVIDER: S-EPMC3988269 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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3D late gadolinium enhancement in a single prolonged breath-hold using supplemental oxygenation and hyperventilation.

Roujol Sébastien S   Basha Tamer A TA   Akçakaya Mehmet M   Foppa Murilo M   Chan Raymond H RH   Kissinger Kraig V KV   Goddu Beth B   Berg Sophie S   Manning Warren J WJ   Nezafat Reza R  

Magnetic resonance in medicine 20131015 3


<h4>Purpose</h4>To evaluate the feasibility of three-dimensional (3D) single breath-hold late gadolinium enhancement (LGE) of the left ventricle (LV) using supplemental oxygen and hyperventilation and compressed-sensing acceleration.<h4>Methods</h4>Breath-hold metrics [breath-hold duration, diaphragmatic/LV position drift, and maximum variation of R wave to R wave (RR) interval] without and with supplemental oxygen and hyperventilation were assessed in healthy adult subjects using a real-time si  ...[more]

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