Ontology highlight
ABSTRACT:
SUBMITTER: Szutorisz H
PROVIDER: S-EPMC3988557 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Szutorisz Henrietta H DiNieri Jennifer A JA Sweet Eric E Egervari Gabor G Michaelides Michael M Carter Jenna M JM Ren Yanhua Y Miller Michael L ML Blitzer Robert D RD Hurd Yasmin L YL
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20140102 6
Recent attention has been focused on the long-term impact of cannabis exposure, for which experimental animal studies have validated causal relationships between neurobiological and behavioral alterations during the individual's lifetime. Here, we show that adolescent exposure to Δ(9)-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, results in behavioral and neurobiological abnormalities in the subsequent generation of rats as a consequence of parental germline exposure t ...[more]