Ontology highlight
ABSTRACT:
SUBMITTER: Takahashi A
PROVIDER: S-EPMC3989250 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
PloS one 20140416 4
Aggressive behavior is widely observed throughout the animal kingdom because of its adaptiveness for social animals. However, when aggressive behavior exceeds the species-typical level, it is no longer adaptive, so there should be a mechanism to control excessive aggression to keep it within the adaptive range. Using optogenetics, we demonstrate that activation of excitatory neurons in the medial prefrontal cortex (mPFC), but not the orbitofrontal cortex (OFC), inhibits inter-male aggression in ...[more]