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Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.

ABSTRACT: A rhesus macaque developed chronic anemia, lymphocytic leukocytopenia, fever, and anorexia while immunodeficient following inoculation with a simian-human immunodeficiency virus.A complete blood count, peripheral blood smear, polymerase chain reaction and gene sequence were performed.Blood smears demonstrated persistent intraerythrocytic piroplasms with rare Maltese cross forms. Babesia microti-like protozoa were confirmed by polymerase chain reaction and sequencing of the 18S ribosomal RNA gene.With continued use of non-human primates as models for human diseases, infection and complications from babesiosis should be monitored.

SUBMITTER: Liu DX

PROVIDER: S-EPMC3989376 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

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Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.

Liu David X DX Gill Amy A Holman Patricia J PJ Didier Peter J PJ Blanchard James L JL Veazey Ronald S RS Lackner Andrew A AA

Journal of medical primatology 20140211 3

<h4>Background</h4>A rhesus macaque developed chronic anemia, lymphocytic leukocytopenia, fever, and anorexia while immunodeficient following inoculation with a simian-human immunodeficiency virus.<h4>Methods</h4>A complete blood count, peripheral blood smear, polymerase chain reaction and gene sequence were performed.<h4>Results</h4>Blood smears demonstrated persistent intraerythrocytic piroplasms with rare Maltese cross forms. Babesia microti-like protozoa were confirmed by polymerase chain re ...[more]

PMID: 24517274

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Project description:Infant temperament is theorized to lay the foundation for adult personality; however, many questions remain regarding personality in infancy, including the number of dimensions, extent to which they are adult-like, and their relation to other outcomes, such as mental and physical health. Here we tested whether adult-like personality dimensions are already present in infancy in a nonhuman primate species. We measured personality and subjective well-being in 7-month-old rhesus macaques (N = 55) using the Hominoid Personality Questionnaire and Subjective Well-Being Questionnaire, both of which were developed for adult primates based on human measures. Multiple human raters, who provided infants with daily care since birth, independently rated each infant. We found high interrater reliability. Results from a parallel analysis and scree plot indicated a five component structure, which, using principal components analysis, we found to be comprised of dimensions relating to Openness (e.g., curiosity, inquisitive, playfulness), Assertiveness (e.g., dominance, bullying, aggressive), Anxiety (e.g., vigilance, fearful), Friendliness (e.g., sociable, affectionate, sympathetic), and Intellect (e.g., organized, not erratic). These components are largely analogous to those in adult macaques, suggesting remarkably stable structural personality components across the lifespan. Infant macaques' subjective well-being positively correlates with Openness and Assertiveness and negatively correlated with Anxiety, similar to findings in adult macaques and other primates. Together, these findings suggest that, in macaques, infant personality dimensions may be conceptually related to adult personality and challenge the view that infant temperament may be disorganized and not as meaningful as adult personality. Further research is necessary to explore the antecedents, predictive validity, and stability of these personality components across situations and with development.

Dataset Information

Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.

Publications

Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.

Similar Datasets

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