Identification of potential microRNA-target pairs associated with osteopetrosis by deep sequencing, iTRAQ proteomics and bioinformatics.
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ABSTRACT:
SUBMITTER: Ou M
PROVIDER: S-EPMC3992578 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Identification of potential microRNA-target pairs associated with osteopetrosis by deep sequencing, iTRAQ proteomics and bioinformatics.
Ou Minglin M Zhang Xiaoqing X Dai Yong Y Gao Jieying J Zhu Mingsong M Yang Xiangchun X Li Yuchao Y Yang Ting T Ding Min M
European journal of human genetics : EJHG 20131002 5
MicroRNAs aberrantly express in many human diseases including some metabolic bone disorders. They have been found to be associated with osteoclast differentiation and function, which makes them attractive candidates for the therapy of bone. However, the potential clinical application of microRNAs in therapeutics rests heavily upon our in-depth understanding of microRNAs and their targets. To identify potential microRNA-target pairs associated with osteopetrosis, we performed a system approach in ...[more]
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