Ontology highlight
ABSTRACT:
SUBMITTER: Romine NM
PROVIDER: S-EPMC3992831 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Molecular and biochemical parasitology 20140101 1
Nematode anthelminthic resistance is widespread for the 3 major drug classes commonly used in agriculture: benzamidazoles, macrocyclic lactones, and nicotinic agonists e.g. levamisole. In parasitic nematodes the genetics of resistance is unknown other than to the benzimidazoles which primarily involve a single gene. In previous work with a levamisole resistant Oesophagostomum dentatum isolate, the nicotinic acetylcholine receptor (nAChR) exhibited decreased levamisole sensitivity. Here, using a ...[more]