Evidence for strain-specific immunity in patients treated for early lyme disease.
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ABSTRACT:
SUBMITTER: Khatchikian CE
PROVIDER: S-EPMC3993397 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
Evidence for strain-specific immunity in patients treated for early lyme disease.
Khatchikian Camilo E CE Nadelman Robert B RB Nowakowski John J Schwartz Ira I Wormser Gary P GP Brisson Dustin D
Infection and immunity 20140113 4
Lyme disease, caused by Borrelia burgdorferi, is the most commonly reported vector-borne disease in the United States. Many patients treated for early Lyme disease incur another infection in subsequent years, suggesting that previous exposure to B. burgdorferi may not elicit a protective immune response. However, identical strains are almost never detected from patients who have been infected multiple times, suggesting that B. burgdorferi exposure may elicit strain-specific immunity. Probabilist ...[more]
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