Ontology highlight
ABSTRACT:
SUBMITTER: Saint M
PROVIDER: S-EPMC3993605 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Saint Malika M Sawhney Sonal S Sinha Ishani I Singh Rana Pratap RP Dahiya Rashmi R Thakur Anushikha A Siddharthan Rahul R Natarajan Krishnamurthy K
Molecular and cellular biology 20140218 9
A common function of the TFIID and SAGA complexes, which are recruited by transcriptional activators, is to deliver TBP to promoters to stimulate transcription. Neither the relative contributions of the five shared TBP-associated factor (TAF) subunits in TFIID and SAGA nor the requirement for different domains in shared TAFs for transcriptional activation is well understood. In this study, we uncovered the essential requirement for the highly conserved C-terminal region (CRD) of Taf9, a shared T ...[more]