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Demonstration of plasmid-mediated drug resistance in Mycobacterium abscessus.


ABSTRACT: Plasmid-mediated kanamycin resistance was detected in a strain of Mycobacterium abscessus subsp. bolletii responsible for a nationwide epidemic of surgical infections in Brazil. The plasmid did not influence susceptibility to tobramycin, streptomycin, trimethoprim-sulfamethoxazole, clarithromycin, or ciprofloxacin. Plasmid-mediated drug resistance has not been described so far in mycobacteria.

SUBMITTER: Matsumoto CK 

PROVIDER: S-EPMC3993635 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Demonstration of plasmid-mediated drug resistance in Mycobacterium abscessus.

Matsumoto Cristianne Kayoko CK   Bispo Paulo José Martins PJ   Santin Katiane K   Nogueira Christiane Lourenço CL   Leão Sylvia Cardoso SC  

Journal of clinical microbiology 20140226 5


Plasmid-mediated kanamycin resistance was detected in a strain of Mycobacterium abscessus subsp. bolletii responsible for a nationwide epidemic of surgical infections in Brazil. The plasmid did not influence susceptibility to tobramycin, streptomycin, trimethoprim-sulfamethoxazole, clarithromycin, or ciprofloxacin. Plasmid-mediated drug resistance has not been described so far in mycobacteria. ...[more]

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