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ABSTRACT:
SUBMITTER: Flory JH
PROVIDER: S-EPMC3996558 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Flory James H JH Small Dylan S DS Cassano Patricia A PA Brillon David J DJ Mushlin Alvin I AI Hennessy Sean S
Journal of comparative effectiveness research 20140101 1
<h4>Aims</h4>To provide evidence on the comparative effectiveness of oral diabetes drug combinations.<h4>Methods</h4>We performed a retrospective, observational cohort study of glycosylated hemoglobin change in outpatients newly exposed to dual- or triple-drug oral diabetes treatment.<h4>Results</h4>Adjusted response to a second drug added to metformin ranged from 0.85 to 1.21% glycosylated hemoglobin decline. Response to a third drug was smaller (0.53-0.91%). Higher baseline glycosylated hemogl ...[more]