Ontology highlight
ABSTRACT:
SUBMITTER: Rizzieri DA
PROVIDER: S-EPMC3996561 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Rizzieri David A DA Johnson Jeffrey L JL Byrd John C JC Lozanski Gerard G Blum Kristie A KA Powell Bayard L BL Shea Thomas C TC Nattam Sreenivasa S Hoke Eva E Cheson Bruce D BD Larson Richard A RA
British journal of haematology 20140115 1
To improve long-term outcomes for Burkitt leukaemia/lymphoma (BL) or aggressive lymphomas in adults, we assessed the benefit of adding rituximab and filgrastim support to a dose-dense modified chemotherapy regimen from the Cancer and Leukemia Group B (CALGB) 9251 trial. One hundred and five patients (aged 19-79 years) were enrolled; 27% were >60 years old; 47% had high or high-intermediate risk by International Prognostic Index (IPI) criteria. Common severe toxicities included stomatitis/upper g ...[more]